The Florida Highway Patrol responded to a fatal crash on Milwaukee Boulevard and Homestead Road in Lehigh Acres.
The Lehigh Acres Fire Department confirms two fatalities. Two other people were injured. One had to be extricated from the vehicle and flown to Lee Memorial Hospital as a trauma alert. The other is in stable condition and also on the way to Lee Memorial.
Firefighters say the crash involved a car and a truck pulling a trailer. The intersection is blocked at this time.